Recognized a GATA3+ TH2 population that expresses the transcription components TCF1 and LEF1 and sustains form 2 inflammation in tissues above a human lifetime, Irrespective of Continual antigen exposure. The complementary “induced self” system of activation states that most cancers cells Show elevated expression of ligands for NK mobile receptors https://directivepublications.org/journal-of-immunology/