Injectable codeine is accessible for subcutaneous or intramuscular injection only; intravenous injection is contraindicated, as this may result in nonimmune mast-cell degranulation and resulting anaphylactoid response. Codeine suppositories may also be marketed in a few countries. In Ireland, new regulations came into effect on one August 2010[ninety] about codeine, as https://www.codeingil.com/