44 Additionally, anergic cells Commonly retain an increased susceptibility to apoptosis Except anti-apoptotic proteins including BCL2 are overexpressed, as is the case for CLL cells.45 Indeed, most main therapeutic innovations happening in the last decade are relevant to the inhibition of BCR and BCL2-mediated signaling. Long-term lymphocytic leukemia is a https://irvingy975wgn3.bloggip.com/profile