In this article, we demonstrate that conolidine, a organic analgesic alkaloid used in common Chinese medication, targets ACKR3, thus offering added evidence of the correlation involving ACKR3 and pain modulation and opening alternate therapeutic avenues for that treatment of Long-term agony. Purely natural agony reduction with no opioids, no https://www.proleviate.com/post/conolidine-for-pain-relief